Proteomics Services | Dalton Bioanalytics
Unlock Deep Protein Insights: Precision Proteomics Services by Dalton Bioanalytics
At Dalton Bioanalytics, our comprehensive precision proteomics services unlock the entire protein landscape. Leveraging advanced mass spectrometry and robust bioinformatics, we deliver deep, unparalleled insights into protein function, dynamics, and interactions, accelerating next-generation therapeutics and reshaping your drug development strategy. For projects that require integrated insights across multiple biological layers, our unique Omni-MS™ platform offers a seamless path for multiomics expansion from a single sample analysis, ensuring a holistic understanding of your research.
Our expert team, with deep cross-disciplinary expertise, collaborates closely with you to design a tailored proteomic approach from the start. Led by Dr. Austin Quach (10+ years in Proteomics, multiomics, LC-MS analysis, and bioinformatics), our scientists bring unparalleled experience across diverse therapeutic areas for both standard and multiomics-integrated projects. We deliver robust, decision-driving data and actionable insights, ensuring your program progresses faster and with unwavering confidence. Contact us today to accelerate your drug discovery with precision proteomics.
From Sample to Insight: Our Integrated Proteomics Workflow
At Dalton Bioanalytics, we provide a truly comprehensive, end-to-end proteomics solution, ensuring seamless execution from your initial project design through to actionable insights. Our integrated workflow means you benefit from unparalleled expertise at every stage, delivering robust and reliable data to drive your research forward. See how our precision process, expertly managed by our scientists including Dr. Austin Quach (10+ years in Proteomics, LC-MS analysis, and bioinformatics), translates into impactful discoveries:
Adapted from Shuken, S. R. (2023). An Introduction to Mass Spectrometry-Based Proteomics. Journal of Proteome Research, 22(6), 2151-2171. https://doi.org/10.1021/acs.jproteome.2c00838
Our quantitative proteomics Services
We offer a full suite of proteomics services to help you gain unparalleled insight into protein expression, function, and modifications. Whether you need discovery proteomics or targeted proteomics, our experienced team and advanced instrumentation can address your unique research challenges.
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Discovery Proteomics
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Achieve deep proteome coverage through shotgun proteomics analysis
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Unbiased approach to identify and quantify thousands of proteins
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Targeted Proteomics
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Precise quantification using SRM/MRM and PRM techniques
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Confirm and validate protein targets with high sensitivity
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Data-Independent Acquisition (DIA)
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Comprehensive proteome analysis with unparalleled depth
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Robust data reproducibility across large sample sets
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Advanced Protein Separation
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Enhanced proteome coverage through sophisticated fractionation methods
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Greater resolution for complex samples
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Post-Translational Modification (PTM) Analysis
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Detect and quantify crucial PTMs (phosphorylation, glycosylation, etc.)
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Understand protein function and regulatory mechanisms
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Biocomputational Analysis
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Leverage our advanced bioinformatics pipelines for actionable insights
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End-to-end data processing, from raw files to biological interpretation
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Our high-throughput mass spectrometry methods allow simultaneous profiling of thousands of proteins per sample, catering to large-scale projects. With state-of-the-art instrumentation and robust QC/QA protocols, we guarantee reliable and reproducible data.
Applications and Benefits of Our Proteomics Services
Accelerated Drug Discovery and Target Identification
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Identify novel drug targets with unmatched precision and sensitivity
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Evaluate drug efficacy and toxicity early in the pipeline
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Inform lead optimization through data-driven protein profiling
Disease Mechanism Elucidation
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Investigate underlying molecular pathways in complex diseases
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Explore protein networks, protein-protein interactions, and pathway dysregulation
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Develop innovative therapeutic strategies based on proteomic insights
Biomarker Discovery and Validation
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Uncover early disease biomarkers for improved diagnosis and prognosis
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Validate biomarkers in clinical trials to stratify patient populations
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Drive personalized medicine approaches
Agricultural and Food Science Advancements
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Enhance crop yield and food quality via comprehensive protein analysis
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Tackle global food security through targeted proteomics research
Why Choose Dalton Bioanalytics as Your Proteomics CRO?
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Expert Team: Our scientists provide unparalleled experience in mass spectrometry and protein chemistry, ensuring reliable and high-quality results for every project, from fundamental proteomics to integrated multiomics.
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Cutting-Edge Technology: We utilize advanced LC-MS/MS systems, high-resolution Orbitrap instruments, and robust data workflows for all our proteomics investigations. For projects requiring broader insights, we seamlessly integrate these capabilities with our unique Omni-MS™ platform to provide comprehensive multiomics analysis."
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Reason: Directly states that your standard tech is used for all proteomics, and then explains how Omni-MS™ integrates for multiomics needs. This precisely addresses your clarification.
Frequently Asked Questions
1. Q: What advanced proteomics analysis options does Dalton Bioanalytics offer for my research?
* A: At Dalton Bioanalytics, we provide a full spectrum of proteomics services including Discovery Proteomics for unbiased protein identification, Targeted Proteomics (SRM/MRM and PRM) for precise quantification, Data-Independent Acquisition (DIA) for comprehensive proteome analysis, Advanced Protein Separation, and Post-Translational Modification (PTM) analysis. Our approaches, supported by our robust data workflows, are tailored to unlock the entire protein landscape, delivering unparalleled insight for your specific project.
2. Q: How does Dalton Bioanalytics' proteomics expertise deliver actionable insights for drug discovery and biomarker development?
* A: Our proteomics services are designed to accelerate your program by providing robust, decision-driving data. We help identify novel drug targets with unmatched precision, evaluate drug efficacy and toxicity early, and inform lead optimization through data-driven protein profiling. For biomarkers, we uncover and validate early disease indicators, significantly advancing personalized medicine and clinical trials from protein function to dynamics and interactions.
3. Q: What makes Dalton Bioanalytics uniquely qualified to provide cutting-edge proteomics services?
* A: Our strength lies in our expert team, led by Dr. Austin Quach, with over 10 years of specialized experience in proteomics, LC-MS analysis, and bioinformatics, ensuring reliable and high-quality results. We leverage state-of-the-art LC-MS/MS systems, high-resolution Orbitrap instruments, and our unique Omni-MS™ platform for comprehensive, high-throughput analysis. Our cross-disciplinary expertise ensures we deliver robust data tailored to your unique research challenges.
4. Q: Do you provide comprehensive bioinformatics support for proteomics data analysis?
* A: Yes, absolutely. Our advanced biocomputational analysis pipelines are integral to every project. We provide end-to-end data processing, in-depth statistical analysis, pathway enrichment, and intuitive data visualization, expertly guiding you from raw data to clear, biologically meaningful results. This ensures you gain actionable insights to propel your program forward.
5. Q: Can Dalton Bioanalytics integrate proteomics data with other omics analyses if needed later in my project?
* A: Yes. While our proteomics services deliver comprehensive protein insights independently, our strength as a one-stop shop lies in our flexibility. Should your project's scope broaden, we can seamlessly integrate proteomics data with metabolomics, lipidomics, and even transcriptomics from the same samples, leveraging our unique Omni-MS™ platform for a holistic and deeper understanding of biological systems without needing multiple CROs. This allows you to start with proteomics and expand your research as needed.
6. Q: What sample types can Dalton Bioanalytics handle for proteomics analysis?
* A: We support a very wide range of sample types, including cell lysates, various tissue samples, and diverse bodily fluids such as blood, urine, and cerebrospinal fluid. We also accommodate more complex environmental and agricultural samples. Our protocols are flexible and tailored to meet the specific requirements of your research.
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