Diagnosing multiple sclerosis is the easy part. Telling a newly diagnosed 30-year-old whether they will still be walking unaided in ten years is not. A retrospective study in Molecular Neurobiology tested whether lipidomics biomarkers taken once, from cerebrospinal fluid drawn at the diagnostic lumbar puncture, carry that missing prognostic signal. The group quantified a single lipid, 18:2 cholesterol ester, in CSF from 115 treatment-naive patients and 57 matched controls, th

```html Blood tests for Alzheimer's disease still lean on amyloid and tau, yet lipid changes surface in neurons long before plaques dominate a scan. A team at China Pharmaceutical University went after that gap. They profiled 156 people spanning normal cognition, amnestic mild cognitive impairment, and Alzheimer's, then built lipidomics biomarkers from two blood compartments at once: plasma and the red blood cell membrane. The payoff is a six-lipid panel that told patients fr