top of page

Spatial Metabolomics Mass Spectrometry Imaging: MALDI vs DESI forHigh-Resolution Tissue Mapping

  • Writer: Seungjun Yeo
    Seungjun Yeo
  • Oct 13, 2025
  • 0 min read
Infographic comparing MALDI and DESI mass spectrometry imaging for spatial metabolomics: MALDI uses matrix-coated cryosections and laser ionization for high spatial resolution but matrix clusters limit m/z < 500; DESI sprays charged solvent without matrix, allows section re-analysis, detects small metabolites, and both generate spectra and ion images for spatial lipidomics and drug mapping.

 
 
logo02_edited.png

California NanoSystems Institute

570 Westwood Plaza
Bldg 114, Rm 6350H, Mail 722710
Los Angeles, California 90095‐7227

Copyright © 2025

Dalton Bioanalytics Inc.

Home

Company

Technology

Application

Analysis Services

Subscribe to Our Newsletter

Thanks for subscribe!

bottom of page